Alessandra Camarca


Name: Alessandra
Surname: Camarca
Skill: Researcher
Phone: (Office) +39 0825 299 361
Phone: (Lab) +39 0825 299 304
Fax: +39 0825 299 641
CNR People WEB Site:
Keywords: Protein structure and stability; Biosensors; Diagnostic tools; POCT;
Curriculum EN: (click here to view it)

Research Activities

Dr. Camarca is an expert in mucosal immunology, in particular in gluten-induced enteropathy (Coeliac Disease). Her research has mainly been focused on gluten immunogenic sequences, cellular biology of gluten-specific T-lymphocytes, immunological potential of alternative cereals for celiac diet, enzymatic strategies for gluten detoxification, anti-inflammatory properties of natural compounds. More recently she has also acquired expertise in fluorescence spectroscopy, applied to the development of biosensors. 

Keywords: Mucosal Immunology, Gluten, Celiac Disease, T cell lines

Research area: OMICS

Key Pubblications


  • Photonic Label-Free Biosensors for Fast and Multiplex Detection of Swine Viral Diseases. Gómez-Gómez, M., Sánchez, C., Peransi, S., Zurita, D., Bellieres, L., Recuero, S., Rodrigo, M., Simón, S., Camarca, A., ….Giusti, A., Griol, A. Sensors, 2022, 22(3), 708
  • Characterization of two NMN deamidase mutants as possible probes for an NMN biosensor. Camarca, A., Minazzato, G., Pennacchio, A., …D’Auria, S., Raffaelli, N. International Journal of Molecular Sciences, 2021, 22(12), 6334
  • Emergent biosensing technologies based on fluorescence spectroscopy and surface plasmon resonance. Camarca, A., Varriale, A., Capo, A., …D’auria, S., Staiano, M. Sensors (Switzerland), 2021, 21(3), pp. 1–35, 906
  • Fluorescence polarization assay to detect the presence of traces of ciprofloxacin. El Kojok, H., El Darra, N., Khalil, M., Pennacchio A., Staiano M., Camarca A., D’Auria, S., Varriale, A. Scientific Reports, 2020, 10(1), 4550
  • In Celiac Disease Patients the In Vivo Challenge with the Diploid Triticum monococcum Elicits a Reduced Immune Response Compared to Hexaploid Wheat. Picascia, S., Camarca, A., Malamisura, M., …Auricchio, R., Gianfrani, C. Molecular Nutrition and Food Research, 2020, 64(11), 1901032
  • The intestinal expansion of TCRγδ+ and disappearance of IL4+ T cells suggest their involvement in the evolution from potential to overt celiac disease. Vitale, S., Santarlasci, V., Camarca, A., …Auricchio, R., Gianfrani, C. European Journal of Immunology, 2019, 49(12), pp. 2222–2234
  • Lack of immunogenicity of hydrolysed wheat flour in patients with coeliac disease after a short-term oral challenge. Mandile, R., Picascia, S., Parrella, C., Camarca, A.,….Gianfrani, C., Auricchio, R. Alimentary Pharmacology and Therapeutics, 2017, 46(4), pp. 440–446
  • Gliadin-reactive T cells in Italian children from preventCD cohort at high risk of celiac disease. Camarca, A., Auricchio, R., Picascia, S.,…Troncone, R., Gianfrani, C. Pediatric Allergy and Immunology, 2017, 28(4), pp. 362–369
  • Gliadin-specific CD8+ T cell responses restricted by HLA class I A0101 and B0801 molecules in celiac disease patients. Picascia, S., Sidney, J., Camarca, A., …Sette, A., Gianfrani, C. Journal of Immunology, 2017, 198(5), pp. 1838–1845
  • Microwave-based treatments of wheat kernels do not abolish gluten epitopes implicated in celiac disease. Gianfrani, C., Mamone, G., la Gatta, B., Camarca A., …Picariello, G., Di Luccia, A. Food and Chemical Toxicology, 2017, 101, pp. 105–113