Virginia Carbone


Name: Virginia
Surname: Carbone
Skill: Researcher
Phone: (Office) +39 0825 299 211
Phone: (Lab) +39 0825 299 204/205
Fax: +39 0825 299 641
CNR People WEB Site:
Keywords: Mass spectrometry; HPLC-MSn; phenolic compounds; Secondary metabolites; antioxidant; Food analysis; Food composition;
Curriculum EN: (click here to view it)

Researcher Activities

Main research activities of Virginia Carbone are focused on the development and application of advanced analytical methodologies based on mass spectrometry in the area of Food Science and Human Health. In particular, she is involved in studies on chemical and biological features of food and medicinal plants with a special focus on the structural characterization of secondary metabolites belonging to different classes by integrating chromatographic techniques (High Performance Liquid Chromatography-HPLC) coupled to UV spectroscopy and/or conventional (LC-MS), tandem (LC-MS/MS) and multistage (LC-MS/MSn) mass spectrometry. The aim of this research activity is the definition of molecular profiles useful for the promotion of food products through the identification of molecules with specific biological activities; comparison of different cultivars; monitoring changes in the qualitative and quantitative profiles during ripening, industrial treatments or in plants subjected to different biotic or abiotic stress conditions; identification of specific biomarkers for the assessment of food authenticity and quality.

Key Publications

  • Vijayalakshmi G., Raja M.M., Naik M.L., Carbone V., Russo G.L., Khan P.S.S.V. “Determination of antioxidant capacity and flavonoid composition of onion (Allium cepa L.) landrace ‘Krishnapuram’ bulb using HPLC-ESI-ITMS” J. Biosci., 46, Issue 3, Article number 58, 2021.
  • Squillaci G., Zannella C., Carbone V., Minasi P., Folliero V., Stelitano D., La Cara F., Galdiero M., Franci G., Morana A. “Grape canes from typical cultivars of campania (Southern italy) as a source of high-value bioactive compounds: Phenolic profile, antioxidant and antimicrobial activities” Molecules, 26, Issue 91, Article number 2746, 2021.
  • Russo, A. Milito, C. Spagnuolo, V. Carbone, A. Rosén, P. Minasi, F. Lauria, G.L. Russo “CK2 and PI3K are direct molecular targets of quercetin in chronic lymphocytic leukaemia” Oncotarget, 8, 42571-42587, 2017.
  • A.M. Salzano, G. Renzone, A. Sobolev, V. Carbone, M. Petriccione, D. Capitani, M. Vitale, G. Novi, N. Zambrano, M.S. Pasquariello, L. Mannina, A. Scaloni “Unveiling kiwifruit metabolite and protein changes in the course of postharvest cold storage” Frontiers in Plant Science, 10, Article number 71, 2019.
  • A.M. Salzano, A. Sobolev, V. Carbone, M. Petriccione, G. Renzone, D. Capitani, M. Vitale, P. Minasi, M.S. Pasquariello, G. Novi, N. Zambrano, M. Scortichini, L. Mannina, A. Scaloni “A proteometabolomic study of Actinidia deliciosa fruit development” Journal of Proteomics, 172, 11-24, 2018.
  • Pace, I. Capotorto, M. Cefola, P. Minasi, N. Montemurro, V. Carbone “Evaluation of quality, phenolic and carotenoid composition of fresh-cut purple Polignano carrots stored in modified atmosphere” J. Food Compos. Anal., 86, 103363, 2020.
  • Squillaci, R. Parrella, V. Carbone, P. Minasi, F. La Cara, A. Morana “Carotenoids from the extreme halophilic archaeon Haloterrigena turkmenica: identification and antioxidant activity” Extremophiles, 21, 933-945, 2017.