{"id":4026,"date":"2015-07-01T12:22:10","date_gmt":"2015-07-01T12:22:10","guid":{"rendered":"http:\/\/lserver.isa.cnr.it\/web\/?page_id=4026"},"modified":"2025-08-01T08:10:51","modified_gmt":"2025-08-01T08:10:51","slug":"maria-cristina-staiano","status":"publish","type":"page","link":"https:\/\/www.isa.cnr.it\/web\/?page_id=4026","title":{"rendered":"Maria Cristina Staiano"},"content":{"rendered":"

\"Donna\"<\/h2>\n
Name: <\/strong>Maria Cristina\r\n<\/pre>\n
Surname: <\/strong>Staiano\r\n<\/pre>\n
Skill<\/b>: Senior Researcher<\/pre>\n
Phone:<\/strong> (Office) +39 0825 299 101<\/pre>\n
Phone:<\/strong> (Lab) +39 0825 299 216\/131<\/pre>\n
Fax:<\/strong> +39 0825 299 641<\/pre>\n
e-mail: maria.staiano<\/strong>@isa.cnr.it<\/h5>\n
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C<\/em><\/strong>NR People<\/em> WEB Site: <\/strong>http:\/\/www.cnr.it\/people\/maria.staiano<\/a><\/h5>\n
Keywords: :<\/span><\/b> Proteins, <\/span>Molecular Biology, Biotechnology, Enzymology, Fuorescence, Food Safety and Food Security.<\/span><\/strong><\/h5>\n
Curriculum EN<\/strong>: (click here to view it)<\/a><\/h5>\n
Researcher Activities<\/h1>\n
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Dr. Maria Staiano is part of Laboratory for Molecular Sensing and she is involved in the study of structural and functional aspects of proteins isolated even from extremophile organisms by the use of advanced methodologies of fluorescence spectroscopy, linear and circular dichroism for the development of new optical biosensors for analytes of high social interest (food safety, clinical chemistry, environment, etc).<\/p>\n
The main interest of the laboratory is on understanding the rules underlying the folding of proteins and how their structure is modified by the interaction with other proteins, nucleic acids and small ligand molecules. To approach these issues we use, and occasionally develop, new, advanced optical methodologies. The acquired knowledge in protein structure is used for the design of innovative diagnostic methods and for other biotechnology applications.<\/p>\n
The focus is to develop and apply advanced luminescence methodologies and optical measurements to solve questions of biochemical and medical interests.\u2028In particular, our interests are focused on the study at a molecular level of the interactions involving proteins, enzymes, nuclei acids as well as small ligand molecules for contributing to shed light to the fields of proteomics, post-proteomics, interatomic and bio\/sensing.\u2028Our lab is equipped with the state-of-art instrumentations for investigating biological interactions by means of FRET, time-resolved FRET, fluorescence polarization, anisotropy decays, fluorescence correlation spectroscopy for single molecule detection, surface plasmon resonance, circular dichroism in the far- and near-UV regions, stopped-flow methodologies, metal enhanced fluorescence.\u2028In addition, the Lab has core collaborations in the fields of bioinformatics, atomic force microscopy, linear spectroscopy, material engineering, and nanotechnology that allow us to handle research projects until they are completely fulfilled.\u2028The Lab is also active in the use of fluorescence to quantify structural features of biological molecules even at nano-scale, and, consequently, to design advanced optical biochips, Lab-on-Chip, or simple disposable biosensors for analyses of high social interest (POCT).\u2028This capability in biophysical methodologies together with expertise in protein biochemistry, molecular genetics and microbiology allows the research team to challenge cutting-edge biochemical questions as well as to rapidly answer to biotechnological requests from SMEs and public institutions.<\/p>\n
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Key Publications<\/h1>\n
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