{"id":3205,"date":"2015-02-20T08:04:04","date_gmt":"2015-02-20T08:04:04","guid":{"rendered":"http:\/\/www.isa.cnr.it\/web\/?page_id=3205"},"modified":"2026-05-18T07:32:18","modified_gmt":"2026-05-18T07:32:18","slug":"gianfranco-mamone","status":"publish","type":"page","link":"https:\/\/www.isa.cnr.it\/web\/?page_id=3205","title":{"rendered":"Gianfranco Mamone"},"content":{"rendered":"<h2 style=\"text-align: left;\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-7409 alignleft\" src=\"http:\/\/www.isa.cnr.it\/web\/wp-content\/uploads\/2014\/11\/Uomo.png\" alt=\"Uomo\" width=\"261\" height=\"303\" srcset=\"https:\/\/www.isa.cnr.it\/web\/wp-content\/uploads\/2014\/11\/Uomo.png 621w, https:\/\/www.isa.cnr.it\/web\/wp-content\/uploads\/2014\/11\/Uomo-259x300.png 259w\" sizes=\"(max-width: 261px) 100vw, 261px\" \/><\/h2>\n<pre style=\"text-align: left;\"><strong>Name: <\/strong>Gianfranco\r\n<\/pre>\n<pre style=\"text-align: left;\"><strong>Surname: <\/strong>Mamone\r\n<\/pre>\n<pre style=\"text-align: left;\"><b>Skill<\/b>: Research Director<\/pre>\n<pre><strong>Phone:<\/strong> (Office)&nbsp;+39 0825 299&nbsp;521<\/pre>\n<pre><strong>Phone:<\/strong> (Lab)&nbsp;+39 0825 299&nbsp;218<\/pre>\n<pre><strong>Fax:<\/strong>&nbsp;+39 0825 299 218<\/pre>\n<h5 style=\"text-align: left;\"><strong>e-mail: gianfranco.mamone@isa.cnr.it<\/strong><\/h5>\n<h5 style=\"text-align: left;\">&nbsp;<\/h5>\n<h5 style=\"text-align: left;\"><strong><em>CNR People<\/em> WEB Site:&nbsp;<\/strong><a href=\"http:\/\/www.cnr.it\/people\/gianfranco.mamone\" target=\"_blank\" rel=\"noopener noreferrer\">http:\/\/www.cnr.it\/people\/gianfranco.mamone<\/a><\/h5>\n<h5 style=\"text-align: left;\"><strong>Keywords:&nbsp;<\/strong><\/h5>\n<h5 style=\"text-align: left;\"><strong>Curriculum EN<\/strong>: <a href=\"https:\/\/www.isa.cnr.it\/web\/wp-content\/uploads\/2026\/05\/CV_Mamone.pdf\" target=\"_blank\" rel=\"noopener\">(click here to view it)<\/a><\/h5>\n<h1 style=\"text-align: center;\">Researcher Activities<\/h1>\n<p data-start=\"0\" data-end=\"283\">Dr. Mamone\u2019s work focuses on the isolation and structural characterization of molecules and macromolecules of interest in food science through proteomic analysis techniques. In particular, Dr. Mamone\u2019s research is mainly centered on the study of proteins from different perspectives:<\/p>\n<ul data-start=\"285\" data-end=\"589\" data-is-last-node=\"\" data-is-only-node=\"\">\n<li data-section-id=\"qb0j6n\" data-start=\"285\" data-end=\"336\">proteomics applied to the study of food proteins;<\/li>\n<li data-section-id=\"14kjqrm\" data-start=\"337\" data-end=\"367\">proteolytic events in foods;<\/li>\n<li data-section-id=\"2po62s\" data-start=\"368\" data-end=\"458\">identification of bioactive sequences generated from food proteins (bioactive peptides);<\/li>\n<li data-section-id=\"12b618y\" data-start=\"459\" data-end=\"526\">characterization of post-translational modifications of proteins;<\/li>\n<li data-section-id=\"ez5jx9\" data-start=\"527\" data-end=\"589\" data-is-last-node=\"\">study of digestion processes in in vitro and in vivo models.<\/li>\n<\/ul>\n<h1 style=\"text-align: center;\">Key Publications<\/h1>\n<p>Mamone G, Nitride C, Picariello G, Addeo F, Ferranti P, Mackie AR. Tracking the fate of pasta (T. durum semolina) immunogenic proteins by in vitro simulated &nbsp;digestion.<\/p>\n<p>J Agric Food Chem. 2015 Feb 14. [<\/p>\n<p>Epub ahead of print] PubMed PMID: 25682706.<\/p>\n<p>&nbsp;<\/p>\n<p>Iacomino G, Fierro O, D&#8217;Auria S, Picariello G, Ferranti P, Liguori C, Addeo F, Mamone G. Structural analysis and Caco-2 cell permeability of the celiac-toxic A-gliadin peptide 31-55.<\/p>\n<p>J Agric Food Chem. 2013 Feb 6;61(5):1088-96.<\/p>\n<p>doi: 10.1021\/jf3045523. Epub 2013 Jan 27. PubMed PMID: 23298305.<\/p>\n<p>&nbsp;<\/p>\n<p>Mamone G, Caira S, Garro G, Mauriello R, Nicolai MA, Picariello G, Calabrese MG, Ferranti P, Chianese L, Addeo P. Challenging the heterogeneity of casein by an IEF\/MALDI-TOF \u201cvirtual 2D-like\u201d approach.<\/p>\n<p>Food Research Internation. 2013 Nov;54(1): 1263-1272<\/p>\n<p>doi:10.1016\/j.foodres.2012.11.038.<\/p>\n<p>Scopus<\/p>\n<p>&nbsp;<\/p>\n<p>Mamone G, Picariello G, Addeo F, Ferranti P.<\/p>\n<p>Proteomic analysis in allergy and intolerance to wheat products.<\/p>\n<p>Expert Rev Proteomics. 2011 Feb;8(1):95-115.<\/p>\n<p>doi: 10.1586\/epr.10.98. Review. PubMed PMID: 21329430.<\/p>\n<p>&nbsp;<\/p>\n<p>Mamone G, Picariello G, Ferranti P, Addeo F.<\/p>\n<p>Hydroxyapatite affinity chromatography for the highly selective enrichment of mono- and multi-phosphorylated peptides in phosphoproteome analysis. Proteomics. 2010 Feb;10(3):380-93. doi: 10.1002\/pmic.200800710. PubMed PMID: 19953538.<\/p>\n<p>&nbsp;<\/p>\n<p>Mamone G, De Caro S, Di Luccia A, Addeo F, Ferranti P.<\/p>\n<p>Proteomic-based analytical approach for the characterization of glutenin subunits in durum wheat.<\/p>\n<p>J Mass Spectrom. 2009 Dec;44(12):1709-23.<\/p>\n<p>doi: 10.1002\/jms.1680. PubMed PMID: 19830788.<\/p>\n<p>&nbsp;<\/p>\n<p>De Caro, S., Ferranti, P., Addeo, F., Mamone, G.<\/p>\n<p>Isolation and characterization of Avenin-like protein type-B from durum wheat (2010)<\/p>\n<p>Journal of Cereal Science, 52 (3), 426-431.<\/p>\n<p>DOI: 10.1016\/j.jcs.2010.07.005<\/p>\n<p>Scopus<\/p>\n<p>&nbsp;<\/p>\n<p>Mamone G, Picariello G, Caira S, Addeo F, Ferranti P.<\/p>\n<p>Analysis of food proteins and peptides by mass spectrometry-based techniques.<\/p>\n<p>J Chromatogr A. 2009<\/p>\n<p>Oct 23;1216(43):7130-42. doi: 10.1016\/j.chroma.2009.07.052. Epub 2009 Aug 3.<\/p>\n<p>Review. PubMed PMID: 19699482.<\/p>\n<p>&nbsp;<\/p>\n<p>Mamone G, Ferranti P, Rossi M, Roepstorff P, Fierro O, Malorni A, Addeo F.<\/p>\n<p>Identification of a peptide from alpha-gliadin resistant to digestive enzymes:<\/p>\n<p>implications for celiac disease.<\/p>\n<p>J Chromatogr B Analyt Technol Biomed Life Sci.2007 Aug 15;855(2):236-41.<\/p>\n<p>Epub 2007 May 18. PubMed PMID: 17544966.<\/p>\n<p>&nbsp;<\/p>\n<p>Mamone G, Addeo F, Chianese L, Di Luccia A, De Martino A, Nappo A, Formisano, A, De Vivo P, Ferranti P.<\/p>\n<p>Characterization of wheat gliadin proteins by combined &nbsp;two-dimensional gel electrophoresis and tandem mass spectrometry.<\/p>\n<p>Proteomics. 2005 Jul;5(11):2859-65.<\/p>\n<p>PMID: 15952231.<\/p>\n<h1 style=\"text-align: center;\">Gruppo di Ricerca<\/h1>\n<p>Gianfranco Mamone<\/p>\n<p>Luigia Di Stasio, fellow<\/p>\n<p>Ilaria Staliano, fellow<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Area di Ricerca : <\/strong><\/p>\n<p><a href=\"http:\/\/www.isa.cnr.it\/web\/?page_id=2527\">OMICS<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Name: Gianfranco Surname: Mamone Skill: Research Director Phone: (Office)&nbsp;+39 0825 299&nbsp;521 Phone: (Lab)&nbsp;+39 0825 299&nbsp;218 Fax:&nbsp;+39 0825 299 218 e-mail: gianfranco.mamone@isa.cnr.it &nbsp; CNR People WEB Site:&nbsp;http:\/\/www.cnr.it\/people\/gianfranco.mamone Keywords:&nbsp; Curriculum EN: (click here to view it) Researcher Activities Dr. Mamone\u2019s work focuses&#8230;<br \/><a class=\"read-more-button\" href=\"https:\/\/www.isa.cnr.it\/web\/?page_id=3205\">Leggi il seguito<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":23,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Gianfranco Mamone - ISTITUTO DI SCIENZE DELL&#039; ALIMENTAZIONE - CNR<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.isa.cnr.it\/web\/?page_id=3205\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Gianfranco Mamone - ISTITUTO DI SCIENZE DELL&#039; 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