{"id":2404,"date":"2014-11-25T17:21:01","date_gmt":"2014-11-25T17:21:01","guid":{"rendered":"http:\/\/www.isa.cnr.it\/web\/?page_id=2404"},"modified":"2022-06-01T12:02:32","modified_gmt":"2022-06-01T12:02:32","slug":"angelo-facchiano","status":"publish","type":"page","link":"https:\/\/www.isa.cnr.it\/web\/?page_id=2404","title":{"rendered":"Angelo Facchiano"},"content":{"rendered":"<h2 style=\"text-align: left;\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-2405 alignleft\" src=\"http:\/\/www.isa.cnr.it\/web\/wp-content\/uploads\/2014\/11\/Angelo_Facchiano.jpg\" alt=\"Angelo_Facchiano\" width=\"241\" height=\"290\"><\/h2>\n<pre style=\"text-align: left;\"><strong>Name: <\/strong>Angelo\r\n<\/pre>\n<pre style=\"text-align: left;\"><strong>Surname: <\/strong>Facchiano\r\n<\/pre>\n<pre style=\"text-align: left;\"><b>Skill<\/b>: Research Director<\/pre>\n<pre><strong>Phone:<\/strong> (Office)&nbsp;+39 0825 299&nbsp;625<\/pre>\n<pre><strong>Phone:<\/strong> (Lab)&nbsp;+39 0825 299&nbsp;651<\/pre>\n<pre><strong>Fax:<\/strong>&nbsp;+39 0825 299 641<\/pre>\n<h5 style=\"text-align: left;\"><strong>e-mail: <a href=\"mailto:angelo.facchiano@isa.cnr.it\" target=\"_blank\" rel=\"noopener\">angelo.facchiano<\/a><\/strong><a href=\"mailto:%20nome.cognome@isa.cnr.it\" target=\"_blank\" rel=\"noopener\">@isa.cnr.it<\/a><\/h5>\n<h5 style=\"text-align: left;\"><strong><em>CNR People<\/em> WEB Site:&nbsp;<\/strong><a href=\"http:\/\/www.cnr.it\/people\/angelo.facchiano\" target=\"_blank\" rel=\"noopener\">http:\/\/www.cnr.it\/people\/angelo.facchiano<\/a><\/h5>\n<h5 style=\"text-align: left;\"><strong>Keywords: <span lang=\"EN-US\">bioinformatics, molecular interaction, protein structure and function<\/span><\/strong><\/h5>\n<h5 style=\"text-align: left;\"><strong>Curriculum EN<\/strong>: <a href=\"http:\/\/www.isa.cnr.it\/cv\/facchiano_angelo\/facchiano_angelo_cv_2021_en.pdf\" target=\"_blank\" rel=\"noopener\">(click here to view it)<\/a><\/h5>\n<h1 style=\"text-align: center;\">Researcher Activities<\/h1>\n<p>Development and application of bioinformatics tools for the study of food-related diseases, molecular mechanisms of the effect of food components on health<\/p>\n<h1 style=\"text-align: center;\">Key Publications<\/h1>\n<ul>\n<li>Giordano D, De Masi L, Argenio MA, Facchiano A. (2021)Structural Dissection of Viral Spike-Protein Binding of SARS-CoV-2 and SARS-CoV-1 to the Human Angiotensin-Converting Enzyme 2 (ACE2) as Cellular Receptor.<br \/>\nBiomedicines, 9(8):1038. doi:10.3390\/biomedicines9081038. PMID: 34440241.<\/li>\n<li>Marabotti A, Del Prete E, Scafuri B, Facchiano A (2021)<br \/>\nPerformance of Web tools for predicting changes in protein stability caused by mutations.<br \/>\nBMC Bioinformatics 22(Suppl 7):345. doi: 10.1186\/s12859-021-04238-w PMID: 34225665.<\/li>\n<li>Giordano D, Facchiano A, D&#8217;Auria S, Loreto F. (2021).<br \/>\nA hypothesis on the capacity of plant odorant-binding proteins to bind volatile isoprenoids based on in silico evidences.<br \/>\nElife 2021 Jun 23;10:e66741. doi: 10.7554\/eLife.66741. PMID: 34161230.<\/li>\n<li>Dotolo S, Cervellera C, Russo M, Russo GL, Facchiano A. (2021)<br \/>\nVirtual Screening of Natural Compounds as Potential PI 3 K-AKT1 Signaling Pathway Inhibitors and Experimental Validation.<br \/>\nMolecules 2021 Jan 18;26(2):492. doi: 10.3390\/molecules26020492. PMID: 33477701<\/li>\n<li>Scafuri B, Bontempo P, Altucci L, De Masi L, Facchiano A. (2020)<br \/>\nMolecular Docking Simulations on Histone Deacetylases (HDAC)-1 and -2 to Investigate the Flavone Binding.<br \/>\nBiomedicines 2020 Dec 4;8(12):E568. doi: 10.3390\/biomedicines8120568. PMID: 33291755<\/li>\n<li>Marabotti A, Scafuri B, Facchiano A. (2020)<br \/>\nPredicting the stability of mutant proteins by computational approaches: an overview.<br \/>\nBrief Bioinform. 2020 Jun 3:bbaa074. doi: 10.1093\/bib\/bbaa074. Online ahead of print. PMID: 32496523<\/li>\n<li>Giordano D, Facchiano A. (2019)<br \/>\nClassification of microbial transglutaminases by evaluation of evolution trees, sequence motifs, secondary structure topology and conservation of potential catalytic residues.<br \/>\nBiochem Biophys Res Commun. 2019, 509(2), 506-513. doi: 10.1016\/j.bbrc.2018.12.121. PMID: 30595384<br \/>\nCorrigendum: Biochem Biophys Res Commun. 2019 Mar 26;511(1):205. doi: 10.1016\/j.bbrc.2019.02.058. PMID: 30777328<\/li>\n<li>De Masi L, Castaldo D, Pignone D, Servillo L, Facchiano A. (2017)<br \/>\nExperimental Evidence and In Silico Identification of Tryptophan Decarboxylase in Citrus Genus.<br \/>\nMolecules 2017 Feb 11;22(2). pii: E272. doi: 10.3390\/molecules22020272.<br \/>\nPMID: 27808487<\/li>\n<li>Scafuri B, Marabotti A, Carbone V, Minasi P, Dotolo S, Facchiano A. (2016)<br \/>\nA theoretical study on predicted protein targets of apple polyphenols and possible mechanisms of chemoprevention in colorectal cancer.<br \/>\nSci Rep. 2016 Sep 2;6:32516. doi: 10.1038\/srep32516.<br \/>\nPMID: 27587238<\/li>\n<li>Romano P, Profumo A, Rocco M, Mangerini R, Ferri F, Facchiano A. (2016)<br \/>\nGeena 2, improved automated analysis of MALDI\/TOF mass spectra.<br \/>\nBMC Bioinformatics 2016 Mar 2;17 Suppl 4:61. doi: 10.1186\/s12859-016-0911-2. PMID: 26961516<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Name: Angelo Surname: Facchiano Skill: Research Director Phone: (Office)&nbsp;+39 0825 299&nbsp;625 Phone: (Lab)&nbsp;+39 0825 299&nbsp;651 Fax:&nbsp;+39 0825 299 641 e-mail: angelo.facchiano@isa.cnr.it CNR People WEB Site:&nbsp;http:\/\/www.cnr.it\/people\/angelo.facchiano Keywords: bioinformatics, molecular interaction, protein structure and function Curriculum EN: (click here to view it)&#8230;<br \/><a class=\"read-more-button\" href=\"https:\/\/www.isa.cnr.it\/web\/?page_id=2404\">Leggi il seguito<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":23,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Angelo Facchiano - ISTITUTO DI SCIENZE DELL&#039; ALIMENTAZIONE - CNR<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.isa.cnr.it\/web\/?page_id=2404\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Angelo Facchiano - ISTITUTO DI SCIENZE DELL&#039; 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