Paola Russo


Direct: +39 0825 299423
Lab: +39 0825 299261
FAX: +39 0825 299423

Short CV

Research Interests

The research activity of Dr. Paola Russo is focused on the interaction between genetic and nutritional factors in the pathogenesis of chronic diseases. The research area primarily involves the investigation of genetic and dietary factors, using epidemiology approaches, in the cause and prevention of cardiovascular disease, renal disease, and other important conditions. She is now evaluating genetic and biological markers of the interaction of nutritional factors with determinants of disease.

She co-ordinates the activity of the risk polymorphism genetic lab (SNPs lab), where genetic variants associated with arterial hypertension, altered renal sodium handling and obesity were identified. More recently, the activity of the SNPs Lab, set up at ISA-CNR by Dr. Paola Russo in 2000, is focused on the evaluation of gene-environment interaction in multi-factorial diseases, in particular cardiovascular diseases, metabolic disorders, childhood and adult obesity, in large samples of children and adult European and multi-ethnic populations, through the characterization and the analysis of risk polymorfisms (SNPs).

Key Publications

Russo P, Siani A, Venezia A, Iacone R, Russo O, Barba G, Cappuccio FP, Strazzullo P.
Interaction between the C(-344)T Polymorphism of CYP11B2 and  Age  in the Regulation of   Blood Pressure and Plasma Aldosterone Levels. Cross-sectional and longitudinal findings of the Olivetti Prospective Heart Study
J Hypertens 2002;20:1785-92. PMID: 12195120


Siani A, Russo P, Cappuccio FP, Iacone R, Venezia A, Russo O, Barba G, Iacoviello L, Strazzullo P.
Combination of renin-angiotensin system polymorphisms is associated with  altered   renal sodium handling and hypertension.
Hypertension 2004;43:598-602. PMID: 14967847


Russo P, Venezia A, Lauria F, Strazzullo P, Cappuccio FP, Iacoviello L, Barba G, Siani A
HindIII(+/-) polymorphism of the  Y chromosome, blood pressure and serum lipids: no evidence of association  in three European populations.
Am J Hypertens 2006;19: 331-8. PMID: 16580565


Barba G. & Russo P.
Dairy foods, dietary calcium and obesity: A short review of the evidence.
Nutr Metab Cardiovasc Dis 2006;16:445-51. PMID: 16928440


Russo P, Lauria F, Loguercio M, Barba G, Arnout J, Cappuccio FP, de Lorgeril M, Donati MB, Iacoviello L, Krogh V, van Dongen M, Siani A, on behalf of the European Collaborative Group of the IMMIDIET Project.
344C/T variant in the promoter of the aldosterone synthase gene (CYP11B2) is associated with metabolic syndrome in men.
Am J Hypertens 2007;20:218-22. PMID: 17261471


Russo P, Strazzullo P, Cappuccio FP, Tregouet DA, Lauria F, Loguercio M, Barba G, Versiero M, Siani A.
Genetic variations at the endocannabinoid type 1 receptor gene (CNR1) are associated with obesity phenotypes in men.
J Clin Endocrinol Metab 2007; 92:2382-6 PMID: 17405839


Russo P, SianiA, MillerMA, KaranamS, EspositoT, GianfrancescoF, BarbaG, LauriaF, StrazzulloP, CappuccioFP.
Genetic variants of Y chromosome are associated with  a protective lipid profile in black men.
Arterioscler Thromb Vasc Biol 2008; 28:1569-74. PMID: 18511697


Russo P, Lauria F, Siani A.
Heritability of body weight: moving beyond genetics.
Nutr Metab Cardiovasc Dis 2010; 20: 691-7. PMID: 21094029

Sánchez J, Priego Y, Picó C, Ahrens W, De Henauw S, Mårild S, Molnár D, Moreno L, Russo P, Siani A, Tornaritis M, Veidebaum T, Palou A.
Blood cells as a source of transcriptional biomarkers of childhood obesity and its related metabolic alterations. Results of the IDEFICS study.
J Clin Endocrin Metabol, 2012;97:E648-E652. PMID: 22278432


Lauria F, Siani A, Bammann K, Foraita R, Huybrechts I, Iacoviello L, Koni AC, Kourides Y, Marild S, Molnar D, Moreno LA, Pigeot I, Pitsiladis YP, Veidebaum T, Russo P; IDEFICS Consortium.
Prospective analysis of the association of a common variant of FTO (rs9939609) with adiposity in children: results of the IDEFICS study.
PLoS One. 2012;7:e48876. PMID: 23155422


Russo P, Siani A.
The role of nuts in the optimal diet: Time for a critical appraisal?
Nutr Metab Cardiovasc Dis 2012; 22:1019-23. PMID: 23199613


Nappo A, Iacoviello L, Fraterman A, Gonzalez-Gil EM, Hadjigeorgiou C, Marild S, Molnar D, Moreno LA, Peplies J, Sioen I, Veidebaum T, Siani A, Russo P.
High-sensitivity C-reactive protein is a predictive factor of adiposity in children: results of the identification and prevention of dietary- and lifestyle-induced health effects in children and infants (IDEFICS) study.
J Am Heart Assoc. 2013;2:e000101 PMID: 23744403


Barba G, Buck C, Bammann K, Hadjigeorgiou C, Hebestreit A, Mårild S, Molnár D, Russo P, Veidebaum T, Vyncke K, Ahrens W, Moreno LA.
Blood pressure reference values for European non-overweight school children: The IDEFICS study.
Int J Obes (Lond). 2014;38 Suppl 2:S48-56. PMID: 25219411



Research Group

Epidemiology & Population Genetics HEALTH