Angelo Facchiano

Senior Researcher, Dr.,Ph.D.

Direct: +39 0825 299625

Lab +39 0825 299651

Fax: +39 0825 781885

Email: angelo.facchiano@isa.cnr.it

Personal Web Page

Research Interests

Research activity is oriented to investigate structure and function of bio-molecules, from molecular mechanisms of human pathologies to food and plant sciences. Techniques are based on bioinformatics, applied to molecular modelling and simulations, molecular interactions, omics data analysis, development of computational tools and data bases.

Key Publications

Key Publications
(2016-2020)

Scafuri B, Bontempo P, Altucci L, De Masi L, Facchiano A. (2020)
Molecular Docking Simulations on Histone Deacetylases (HDAC)-1 and -2 to Investigate the Flavone Binding.
Biomedicines 2020 Dec 4;8(12):E568. doi: 10.3390/biomedicines8120568.

Facchiano A, Facchiano F, Facchiano A. (2020)
An investigation into the molecular basis of cancer comorbidities in coronavirus infection.
FEBS Open Bio 2020 Sep 24:10.1002/2211-5463.12984. doi: 10.1002/2211-5463.12984.

Facchiano, A., Heider, D., Chicco, D., eds. (2020). Artificial Intelligence Bioinformatics: Development and Application of Tools for Omics and Inter-Omics Studies. Lausanne: Frontiers Media SA. doi: 10.3389/978-2-88963-752-2

Marabotti A, Scafuri B, Facchiano A. (2020)
Predicting the stability of mutant proteins by computational approaches: an overview.
Brief Bioinform. 2020 Jun 3:bbaa074. doi: 10.1093/bib/bbaa074.

Facchiano A, Pignone D, Servillo L, Castaldo D, De Masi L. (2019)
Structure and Ligands Interactions of Citrus Tryptophan Decarboxylase by Molecular Modeling and Docking Simulations.
Biomolecules 2019 Mar 26;9(3). pii: E117. doi: 10.3390/biom9030117.

Giordano D, Facchiano A. (2019)
Classification of microbial transglutaminases by evaluation of evolution trees, sequence motifs, secondary structure topology and conservation of potential catalytic residues.
Biochem Biophys Res Commun. 2019, 509(2), 506-513. doi: 10.1016/j.bbrc.2018.12.121.
Corrigendum: Biochem Biophys Res Commun. 2019 Mar 26;511(1):205. doi: 10.1016/j.bbrc.2019.02.058.

Dubey A, Dotolo S, Ramteke PW, Facchiano A, Marabotti A. (2019)
Searching for Chymase Inhibitors among Chamomile Compounds Using a Computational-Based Approach.
Biomolecules 2019 9(1), 5. doi: 10.3390/biom9010005.

Del Prete E, Facchiano A, Liò P. (2018)
Bioinformatics methodologies for coeliac disease and its comorbidities.
Briefing in Bioinformatics 2018 Nov. 16 doi: 10.1093/bib/bby109.

d’Acierno A, Scafuri B, Facchiano A, Marabotti A. (2018)
The evolution of a Web resource: The Galactosemia Proteins Database 2.0.
Hum Mutat. 2018;39(1):52-60. doi: 10.1002/humu.23346.

Scafuri B, Marabotti A, Carbone V, Minasi P, Dotolo S, Facchiano A. (2016)
A theoretical study on predicted protein targets of apple polyphenols and possible mechanisms of chemoprevention in colorectal cancer.
Sci Rep. 2016 Sep 2;6:32516. doi: 10.1038/srep32516.

Research Group

Bioinformatics and Computational Biology

Research Area: OMICS